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Description

Molecular mechanisms of cisplatin resistance

The nucleophile penicillamine is able to ameliorate the impact of acute treatment with H 2 O 2 on oocytes Taken together, our data raise the intriguing prospect that the structural perturbation of tubulin that is induced by 4-HNE adduction may, at least in part, contribute to increased aneuploidy rates observed in oocytes exposed to elevated levels of OS